a Record control number 000269018100055

a ISSN 0970-7077

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QD31.2

b Item number .S96 2009

a Personal name Kiraz, Aşkın,

a Title Synthesis and Characterization of Crown Ethers.

h Medium Electronic Document

c Statement of responsibility, etc Askin Kiraz, Mustafa Yıldız, Başaran Dülger.

b Name of publisher, distributor, etc Asian Journal Of Chemistry,

c Date of publication, distribution, etc 2009.

a Place of publication, distribution, etc Ghaziabad :

a Summary, etc Crown ether ligands of Schiff base type (6-17) have been synthesized by the reaction of 2-hydroxybenzaidehyde, 2-hydroxy-5-methoxybenzaldehyde 2-hydroxy-5-bromobenzaldehyde, 2-hydroxy-5-chlorobenzaldehyde, 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-1-naphthaldehyde with 6,7,8,14-tetrahydrodibenzo[f,i][ 1,5]dioxecine-2,12-diamine (4) and 7,9,10,16-tetrahydro-6H-dibenzo[h,k][ 1,4,7]-trioxacyclododecine-2,14-diamine (5). The structures of Schiff base crown ethers have been investigated by elemental analysis, IR, UV-visible, (1)H NMR, (13)C NMR and MS spectroscopic data. In solution, all Schiff bases exist as equilibrium mixtures of enol-imine and keto-imine tautomers. For four Schiff bases (10, 11, 16, 17). the keto-imine form has been found to be dominant in the DMSO. The antimicrobial activities of the compounds are evaluated using disk diffusion method in dimethyl sulfoxide (DMSO) against 9 bacteria and 5 yeast. cultures. The obtained results from disk diffusion method are assessed in side-by-side comparison with those of penicillin-G, ampicillin, cefotaxime, vancomycin, oflaxacin, tetracycline 8 antibacterial agents and nystatin, ketaconazole and clotrimazole as commercial antifungal agents. In most cases, the compounds show broad-spectrum (Grain-positive and Gram-negative bacteria) activities that are comparatively either, slightly less active or equipotent to, antimicrobial agents in the comparison tests.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Chemistry

a Topical term or geographic name as entry element Crown ether

a Topical term or geographic name as entry element Schiff base

a Topical term or geographic name as entry element Antimicrobial Activity

g Relationship information JUN-JUL 2009, Vol 21 Issue 6, p4495-4507

x International Standard Serial Number 0970-7077

a Main entry heading Asian Journal Of Chemistry