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Tissue Doppler and myocardial deformation imaging to detect myocardial dysfunction in pediatric cancer patients treated with high doses of anthracyclines (Yagci-Kupeli, B)
Bibliographical information (record 264629)
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Tissue Doppler and myocardial deformation imaging to detect myocardial dysfunction in pediatric cancer patients treated with high doses of anthracyclines
Author:
 Yagci-Kupeli, B Search Author in Amazon Books

Publisher:
Wiley-Blackwell,
Edition:
 2012.
Classification:
 QZ200
URL:
http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1111/j.1743-7563.2012.01566.x
Detailed notes
    - Aim To detect subtle changes in myocardial function in pediatric cancer patients treated with high dose anthracyclines.Methods In all, 19 pediatric cancer patients with no cardiotoxicity findings treated with a cumulative anthracycline dose of =350?mg/m2 and healthy participants of the same age were included in the study. Transthoracic echocardiography measurements, pulsed-wave tissue Doppler from the basal portions of all walls and strain and strain rate imaging of all walls from basal portion were obtained.Results A total of 19 patients (13 boys and six girls) and 17 participants (10 boys and seven girls) in the control group were enrolled. Three patients had subnormal ejection fraction (EF) and fractional shortening (FS) values. There was no significant difference in EF and FS between the two groups. The left ventricle isovolumic relaxation time was prolonged (P?=?0.02) and the mitral color propagation velocity was decreased in patients (P?=?0.001). Peak systolic strain and strain rates of the right ventricle, septal, lateral and inferior wall basal region of the left ventricle were significantly lower in patients than controls (all P?
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NEU Grand LibraryOnline (QZ200 .T57 2012)
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